Wednesday 16 May 2012

arformoterol inhalation


Generic Name: arformoterol inhalation (ar for MOE ter ole)

Brand Names: Brovana


What is arformoterol inhalation?

Arformoterol is a bronchodilator. It works by relaxing muscles in the airways to improve breathing.


Arformoterol inhalation is used to prevent bronchoconstriction in people with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. Arformoterol will not treat a bronchospasm attack that has already begun.


Arformoterol may also be used for purposes not listed in this medication guide.


What is the most important information I should know about arformoterol inhalation?


Do not use arformeterol inhalation to treat a bronchospasm attack that has already begun. Call your doctor right away if you feel that this medicine is not working as well as usual, or if you think you need to use more than usual. An increased need for medication could be an early sign that your condition is getting worse. Salmeterol, a medicine similar to arformoterol, has been shown to increase the risk of asthma-related death. It is not known whether arformoterol could cause this same effect in people with chronic obstructive pulmonary disease. Use only the prescribed dose of this medication, and do not use it for longer than your doctor recommends. Follow all patient instructions for safe use. Talk with your doctor about your individual risks and benefits of using arformoterol inhalation.

What should I discuss with my healthcare provider before using arformoterol inhalation?


You should not use this medication if you are allergic to arformoterol. Salmeterol, a medicine similar to arformoterol, has been shown to increase the risk of asthma-related death. It is not known whether arformoterol could cause this same effect in people with chronic obstructive pulmonary disease. Use only the prescribed dose of this medication, and do not use it for longer than your doctor recommends. Follow all patient instructions for safe use. Talk with your doctor about your individual risks and benefits of using arformoterol inhalation.

To make sure you can safely use arformoterol, tell your doctor if you have any of these other conditions:



  • heart disease, a heart rhythm disorder, or high blood pressure;




  • epilepsy or other seizure disorder;




  • diabetes;




  • glaucoma;




  • a thyroid disorder;



  • liver disease; or

  • a personal or family history of "Long QT syndrome."


FDA pregnancy category C. It is not known whether arformoterol will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether arformoterol passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to anyone under 18 years old without your doctor's advice.

How should I use arformoterol inhalation?


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.


This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.


Do not use arformoterol inhalation to treat a sudden bronchospasm attack. It will not work fast enough. Use only a fast-acting inhalation medication. If you were switched from a short-acting bronchodilator to arformoterol inhalation, stop using the other bronchodilator and use it only for a sudden bronchospasm attack. Short-acting bronchodilators include albuterol (Proventil, Ventolin, Combivent), bitolterol (Tornalate), levalbuterol (Xopenex), metaproterenol (Alupent, Metaprel), or pirbuterol (Maxair).

Arformoterol solution for inhalation is for use only with a standard jet nebulizer machine connected to an air compressor. Do not mix arformoterol with other medicines in the nebulizer. Do not take this medicine by mouth or swallow it.


To use the solution with a nebulizer:



  • Open the foil pouch and squeeze all of the medicine out into the chamber of the nebulizer. Attach the mouthpiece or face mask to the drug chamber. Then, attach the drug chamber to the compressor.




  • Sit upright in a comfortable position. Place the mouthpiece into your mouth or put the face mask on, covering your nose and mouth. Turn on the compressor.




  • Breathe in slowly and evenly until you have inhaled all of the medicine (usually 5 to 10 minutes). The treatment is complete when no more mist is formed by the nebulizer and the drug chamber is empty.




  • Clean the nebulizer after each use. Follow the cleaning directions that came with your nebulizer.




Call your doctor right away if you feel that this medicine is not working as well as usual, or if you think you need to use more than usual. An increased need for medication could be an early sign that your condition is getting worse.

COPD is usually treated with a combination of different drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice.


Keep this medicine in the foil pouch until you are ready to use it. Once a pouch is opened, you must use the medicine right away. Throw the empty pouch away where children and pets cannot get to it.


Store the foil pouches in the refrigerator but do not allow them to freeze. You may store the foil pouches at room temperature but you must use them within 6 weeks. Store the single-use vials at room temperature and protect them from heat and light. Do not use any medicine if it does not look clear and colorless in the vial.

What happens if I miss a dose?


Skip the missed dose and wait until your next regularly scheduled dose. Do not use two doses at the same time. It is important to use arformoterol inhalation regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of arformoterol inhalation can be fatal.

Overdose symptoms may include chest pain, fast or irregular heartbeats, nervousness, tremor, muscle cramps, feeling light-headed, and fainting.


What should I avoid while using arformoterol inhalation?


Do not use a second long-acting inhaled bronchodilator such as formoterol (Foradil, Perforomist, Symbicort) or salmeterol (Serevent, Advair) unless your doctor has told you to.


Arformoterol inhalation side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

  • bronchospasm (wheezing, chest tightness, trouble breathing);




  • chest pain, fast or pounding heart beats, restless feeling, tremor;




  • feeling short of breath, even with mild exertion;




  • swelling, rapid weight gain;




  • white patches or sores inside your mouth or on your lips; or




  • dry mouth, increased thirst, drowsiness, restless feeling, confusion, nausea, vomiting, increased urination, muscle pain or weakness, fast heart rate, feeling light-headed, or fainting.



Less serious side effects may include:



  • weakness; headache, sleep problems (insomnia);




  • nausea, vomiting, diarrhea;




  • leg cramps;




  • fever;




  • stuffy nose; or




  • hoarseness or deepened voice.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Arformoterol inhalation Dosing Information


Usual Adult Dose for Chronic Obstructive Pulmonary Disease -- Maintenance:

15 micrograms by nebulization twice a day (morning and evening). A total daily dose greater than 30 micrograms is not recommended.


What other drugs will affect arformoterol inhalation?


Tell your doctor about all other medicines you use, especially:



  • aminophylline (Truphylline) or theophylline (Elixophyllin, Respbid, Slo-Bid, Theo-Dur, Uniphyl);




  • an antibiotic such as azithromycin (Zithromax), clarithromycin (Biaxin), erythromycin (E-Mycin, E.E.S., Erythrocin, Ery-Tab), or telithromycin (Ketek);




  • an antidepressant such as amitriptyline (Elavil, Etrafon), clomipramine (Anafranil), desipramine (Norpramin), imipramine (Janimine, Tofranil), or nortriptyline (Pamelor);




  • a beta-blocker such as atenolol (Tenormin), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), sotalol (Betapace), and others;




  • a diuretic (water pill) such as amiloride (Midamor, Moduretic), furosemide (Lasix), hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Lopressor, Vasoretic, Zestoretic), spironolactone (Aldactazide, Aldactone), triamterene (Dyrenium, Maxzide, Dyazide), and others;




  • heart rhythm medicine such as amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), disopyramide (Norpace), procainamide (Procan, Pronestyl), or quinidine (Quin-G);




  • an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate);




  • narcotic medication such as fentanyl (Actiq, Duragesic, Ionsys), hydrocodone (Lortab, Vicodin), hydromorphone (Dilaudid), methadone (Dolophine, Methadose), morphine (Kadian, MS Contin), oxycodone (OxyContin, Percocet), propoxyphene (Darvocet, Darvon); or




  • steroids (prednisone and others).



This list is not complete and other drugs may interact with arformoterol. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More arformoterol inhalation resources


  • Arformoterol inhalation Side Effects (in more detail)
  • Arformoterol inhalation Dosage
  • Arformoterol inhalation Use in Pregnancy & Breastfeeding
  • Arformoterol inhalation Drug Interactions
  • Arformoterol inhalation Support Group
  • 3 Reviews for Arformoterol - Add your own review/rating


Compare arformoterol inhalation with other medications


  • COPD, Maintenance


Where can I get more information?


  • Your pharmacist can provide more information about arformoterol inhalation.

See also: arformoterol side effects (in more detail)


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