Online PLR Articles Directory South Africa: Haldol Intramuscular

Generic Name: haloperidol (Intramuscular route)

hal-oh-PER-i-dol

Intramuscular route(Solution)

Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death compared to placebo. Although the causes of death in clinical trials were varied, most of the deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature. Observational studies suggest that antipsychotic drugs may increase mortality. It is unclear from these studies to what extent the mortality findings may be attributed to the antipsychotic drug as opposed to patient characteristics. Haloperidol injection is not approved for the treatment of patients with dementia-related psychosis .

Intramuscular route(Injectable)

Elderly patients with dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk of death compared to placebo. Although the causes of death in clinical trials were varied, most of the deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature. Observational studies suggest that antipsychotic drugs may increase mortality. It is unclear from these studies to what extent the mortality findings may be attributed to the antipsychotic drug as opposed to patient characteristics. Haloperidol decanoate is not approved for the treatment of patients with dementia-related psychosis .

Commonly used brand name(s)

In the U.S.

Haldol

Haldol Decanoate

Available Dosage Forms:

Solution

Suspension

Therapeutic Class: Antipsychotic

Pharmacologic Class: Dopamine Antagonist

Chemical Class: Butyrophenone

Uses For Haldol

Haloperidol injection is used to treat nervous, emotional, and mental conditions (e.g., schizophrenia). It is also used to control the symptoms of Tourette's disorder. This medicine should not be used to treat behavior problems in older adult patients who have dementia.

This medicine is available only with your doctor's prescription.

Before Using Haldol

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of haloperidol injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of haloperidol injection in the elderly. However, elderly women are more likely to have a side effect called tardive dyskinesia, and elderly patients are more likely to have age-related heart problems, which may require an adjustment in the dose for patients receiving haloperidol injection.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Bepridil

Cisapride

Dronedarone

Levomethadyl

Mesoridazine

Metoclopramide

Pimozide

Sparfloxacin

Terfenadine

Thioridazine

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acecainide

Ajmaline

Alfuzosin

Amiodarone

Amisulpride

Amitriptyline

Amoxapine

Apomorphine

Aprindine

Arsenic Trioxide

Asenapine

Astemizole

Azimilide

Azithromycin

Bretylium

Chloral Hydrate

Chloroquine

Chlorpromazine

Ciprofloxacin

Citalopram

Clarithromycin

Clomipramine

Clozapine

Crizotinib

Dalfopristin

Dasatinib

Desipramine

Dibenzepin

Disopyramide

Dofetilide

Dolasetron

Doxepin

Droperidol

Encainide

Enflurane

Erythromycin

Flecainide

Fluconazole

Fluoxetine

Foscarnet

Gatifloxacin

Gemifloxacin

Granisetron

Halofantrine

Halothane

Hydromorphone

Hydroquinidine

Ibutilide

Imipramine

Isoflurane

Isradipine

Ketoconazole

Lapatinib

Levofloxacin

Lidoflazine

Lithium

Lopinavir

Lorcainide

Lumefantrine

Mefloquine

Methadone

Milnacipran

Moxifloxacin

Nilotinib

Norfloxacin

Nortriptyline

Octreotide

Ofloxacin

Ondansetron

Paliperidone

Paroxetine

Pazopanib

Pentamidine

Perflutren Lipid Microsphere

Pirmenol

Posaconazole

Prajmaline

Probucol

Procainamide

Prochlorperazine

Promethazine

Propafenone

Propranolol

Protriptyline

Quetiapine

Quinidine

Quinine

Quinupristin

Ranolazine

Risperidone

Salmeterol

Saquinavir

Sematilide

Sertindole

Sodium Phosphate

Sodium Phosphate, Dibasic

Sodium Phosphate, Monobasic

Solifenacin

Sorafenib

Sotalol

Spiramycin

Sulfamethoxazole

Sultopride

Sunitinib

Tedisamil

Telavancin

Telithromycin

Tetrabenazine

Toremifene

Tramadol

Trazodone

Trifluoperazine

Trimethoprim

Trimipramine

Vandetanib

Vardenafil

Vasopressin

Vemurafenib

Venlafaxine

Voriconazole

Ziprasidone

Zolmitriptan

Zotepine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Benztropine

Betel Nut

Bupropion

Buspirone

Carbamazepine

Dextromethorphan

Fluvoxamine

Methyldopa

Nefazodone

Olanzapine

Procyclidine

Rifampin

Rifapentine

Tacrine

Trihexyphenidyl

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of haloperidol

This section provides information on the proper use of a number of products that contain haloperidol. It may not be specific to Haldol. Please read with care.

A nurse or other trained health professional will give you this medicine. This medicine is given as a shot into one of your muscles.

Your doctor may give you a few doses of this medicine until your condition improves, and then switch you to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Precautions While Using Haldol

It is very important that your doctor check your progress while you receive this medicine to allow for changes in your dose and help reduce any unwanted effects.

Contact your doctor as soon as possible if you have chest pain or discomfort, a fast heartbeat, trouble with breathing, or fever and chills. These may be symptoms of a very serious problem with your heart.

This medicine may cause tardive dyskinesia (a movement disorder). Check with your doctor right away if you have any of the following symptoms while using this medicine: lip smacking or puckering, puffing of the cheeks, rapid or worm-like movements of the tongue, uncontrolled chewing movements, or uncontrolled movements of the arms and legs.

Check with your doctor right away if you have any of the following symptoms while receiving this medicine: convulsions (seizures); difficulty with breathing; a fast heartbeat; a high fever; high or low blood pressure; increased sweating; loss of bladder control; severe muscle stiffness; unusually pale skin; or tiredness. These could be symptoms of a serious condition called neuroleptic malignant syndrome (NMS).

This medicine will often make you sweat less, causing your body temperature to increase. Use extra care not to become overheated during exercise or hot weather while you are using this medicine, since overheating may result in heat stroke. Also, hot baths or saunas may make you feel dizzy or faint while you are using this medicine.

This medicine may cause some people to become dizzy, drowsy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.

Dizziness, lightheadedness, or fainting may occur, especially when you get up suddenly from a lying or sitting position. Getting up slowly may help. If this problem continues or gets worse, check with your doctor.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; medicine for seizures or barbiturates; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using this medicine.

Haloperidol injection can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. If you can, avoid people with infections. Check with your doctor right away if you think you are getting an infection, or if you have a fever or chills, a cough or hoarseness, lower back or side pain, or painful or difficult urination.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Haldol Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known

Abdominal or stomach pain

anxiety

black, tarry stools

bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, or warmth at injection site

blurred vision

chest pain

chills

clay-colored stools

cold sweats

coma

confusion

continuing nausea or vomiting

convulsions

cool, pale skin

cough or hoarseness

dark urine

decrease in frequency of urination

decrease in urine volume

decreased urine output

depression

difficulty in passing urine (dribbling)

difficulty with breathing

difficulty with speaking

dizziness

dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly

drooling

dry mouth

eye pain

fainting

false or unusual sense of well-being

fast, pounding, or irregular heartbeat or pulse

fever

fever with or without chills

flushed, dry skin

fruit-like breath odor

general feeling of illness

general feeling of tiredness or weakness

headache

high fever

high or low blood pressure

hot, dry skin

hyperventilation

inability to move the eyes

inability to sit still

increase in the frequency of seizures

increased blinking or spasms of the eyelid

increased hunger

increased sweating

increased thirst

increased urination

irregular heartbeat recurrent

irritability

itching

lack of sweating

lip smacking or puckering

loss of appetite

loss of bladder control

loss of consciousness

lower back or side pain

muscle weakness

muscle pain or cramps

muscle trembling, jerking, or stiffness

nausea or vomiting

need to keep moving

nervousness

nightmares

noisy breathing

painful or difficult urination

pale skin

pounding in the ears

puffing of the cheeks

rapid or worm-like movements of the tongue

rash

restlessness

seizures

severe muscle stiffness

shakiness

shaking

shortness of breath

shuffling walk

slurred speech

sore throat

sores, ulcers, or white spots on the lips or in the mouth

sticking out of the tongue

stiffness of the limbs

sweating

swelling of the face, ankles, or hands

swollen glands

tightness in the chest

tiredness and weakness

total body jerking

trouble with breathing, speaking, or swallowing

trouble with sleeping

troubled breathing with exertion

twisting movements of the body

uncontrolled chewing movements

uncontrolled twisting movements of the face, neck, trunk, arms, or legs

unexplained weight loss

unpleasant breath odor

unusual bleeding or bruising

unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

unusual facial expressions

unusual tiredness or weakness

unusually pale skin

vomiting

vomiting of blood

weakness of the arms and legs

wheezing

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

Acid or sour stomach

acne or pimples

belching

blindness

blurred vision or any other change in vision

decreased interest in sexual intercourse

decreased vision

difficulty having a bowel movement (stool)

disturbed color perception

double vision

drowsiness

feeling of constant movement of self or surroundings

fullness or swelling of the breasts

halos around lights

heartburn

inability to have or keep an erection

increased in sexual ability, desire, drive, or performance

increased interest in sexual intercourse

increased sensitivity of the skin to sunlight

increased watering of the mouth

indigestion

loss in sexual ability, desire, drive, or performance

loss of hair

menstrual changes

night blindness

overbright appearance of lights

pain or tenderness of the breasts

painful or prolonged erection of the penis

redness or other discoloration of the skin

sensation of spinning

severe sunburn

sleeplessness

stomach discomfort, upset, or pain

swelling of the breasts or breast soreness in both females and males

tunnel vision

unable to sleep

unusual secretion of milk

weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Haldol Intramuscular side effects (in more detail)

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More Haldol Intramuscular resources

Haldol Intramuscular Side Effects (in more detail)
Haldol Intramuscular Use in Pregnancy & Breastfeeding
Drug Images
Haldol Intramuscular Drug Interactions
Haldol Intramuscular Support Group
9 Reviews for Haldol Intramuscular - Add your own review/rating

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Online PLR Articles Directory South Africa

Thursday 5 April 2012

Haldol Intramuscular