Xedec II

Generic Name: guaifenesin and phenylephrine (gwye FEN e sin and FEN il EFF rin)

Brand Names: Aldex G, Aquatab D, Crantex, D-Phen 1000, D-Tab, Deconex, Deconsal II, Deconsal Pediatric, Despec, Donatussin Drops, Duomax, Duraphen 1000, Duraphen II, Duratuss, Dynex LA, ExeTuss, Extendryl G, Fenesin PE IR, Genexa LA, Gentex LA, Gilphex TR, Guaiphen-D 1200, Guaiphen-D 600, Guaiphen-PD, Guiadex PD, Guiatex PE, J-Max, Liquibid D-R, Liquibid-D, Liquibid-PD, Lusonex, Maxiphen, Medent-PE, MontePhen, Mucinex Children's Cold, Mucus Relief Sinus, Mydex, Nariz, Nasex, Nescon-PD, Nexphen PD, Norel EX, PE-Guai, Pendex, Prolex D, Refenesen PE, Reluri, Rescon-GG, Respa-PE, Robitussin Head & Chest Congestion, Simuc, Simuc-GP, Sina-12X, Sinupan, SINUvent PE, Sitrex PD, Sudafed PE Non-Drying Sinus, Sudex, Triaminic Chest & Nasal Congestion, Visonex, Wellbid-D, Xedec, Xedec II, Xpect-PE, Zotex GPX

What is Xedec II (guaifenesin and phenylephrine)?

There are many brands and forms of guaifenesin and phenylephrine available and not all brands are listed on this leaflet.

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of guaifenesin and phenylephrine is used to treat stuffy nose and sinus congestion, and to reduce chest congestion caused by the common cold or flu.

Guaifenesin and phenylephrine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Xedec II (guaifenesin and phenylephrine)?

There are many brands and forms of guaifenesin and phenylephrine available and not all brands are listed on this leaflet.

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Ask a doctor or pharmacist before using any other cough, cold, or allergy medicine. Guaifenesin and phenylephrine are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains guaifenesin or phenylephrine.

What should I discuss with my healthcare provider before taking Xedec II (guaifenesin and phenylephrine)?

You should not use this medication if you are allergic to guaifenesin or phenylephrine, or to other decongestants, diet pills, stimulants, or ADHD medications. Do not use guaifenesin and phenylephrine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. Serious, life threatening side effects can occur if you use guaifenesin and phenylephrine before the MAO inhibitor has cleared from your body.

Ask a doctor or pharmacist if it is safe for you to take this medication if you have:

• 
  

  heart disease or high blood pressure;

  
  


• 
  

  diabetes;

  
  


• 
  

  circulation problems;

  
  


• 
  

  glaucoma;

  
  


• 
  

  overactive thyroid; or

  
  


• 
  

  enlarged prostate or problems with urination.

  
  

It is not known if this medication may be harmful to an unborn baby. Do not use this medication without your doctor's advice if you are pregnant. This medication passes into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

How should I take Xedec II (guaifenesin and phenylephrine)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cold medicine is usually taken only for a short time until your symptoms clear up.

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not crush, chew, break, or open an extended-release tablet or capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time. Take guaifenesin and phenylephrine with food if it upsets your stomach. Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash. Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication. Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Since cough or cold medicine is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, numbness or tingly feeling, dizziness, and feeling restless or nervous.

What should I avoid while taking Xedec II (guaifenesin and phenylephrine)?

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of guaifenesin and phenylephrine. Ask a doctor or pharmacist before using any other cough, cold, or allergy medicine. Guaifenesin and phenylephrine are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains guaifenesin or phenylephrine.

Avoid taking this medication with diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

Xedec II (guaifenesin and phenylephrine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

• 
  

  fast, pounding, or uneven heartbeat;

  
  


• 
  

  severe dizziness, anxiety, restless feeling, or nervousness;

  
  


• 
  

  easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms;

  
  


• 
  

  dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure); or

  
  


• 
  

  nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

  
  

Less serious side effects may include:

• 
  

  vomiting, upset stomach;

  
  


• 
  

  warmth, tingling, or redness under your skin;

  
  


• 
  

  feeling excited or restless (especially in children);

  
  


• 
  

  sleep problems (insomnia);

  
  


• 
  

  skin rash or itching;

  
  


• 
  

  headache; or

  
  


• 
  

  dizziness.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Xedec II (guaifenesin and phenylephrine)?

Ask a doctor or pharmacist if it is safe for you to take guaifenesin and phenylephrine if you are also using any of the following drugs:

• 
  

  medicines to treat high blood pressure;

  
  


• 
  

  a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Dutoprol, Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others; or

  
  


• 
  

  an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), doxepin (Sinequan, Silenor), desipramine (Norpramin), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), and others.

  
  

This list is not complete and other drugs may interact with guaifenesin and phenylephrine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Xedec II resources

• Xedec II Side Effects (in more detail)
• Xedec II Use in Pregnancy & Breastfeeding
• Xedec II Drug Interactions
• Xedec II Support Group
• 0 Reviews for Xedec II - Add your own review/rating

• Crantex Prescribing Information (FDA)


• Despec Drops MedFacts Consumer Leaflet (Wolters Kluwer)


• Entex LA Sustained-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)


• Gentex LA Sustained-Release Tablets (12 Hour) MedFacts Consumer Leaflet (Wolters Kluwer)


• Guiatex PE Prescribing Information (FDA)


• Lusonex Controlled-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)


• Rescon-GG Liquid MedFacts Consumer Leaflet (Wolters Kluwer)


• Sina-12X Suspension MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Xedec II with other medications

• Cough and Nasal Congestion
• Sinus Symptoms

Where can I get more information?

• Your pharmacist can provide more information about guaifenesin and phenylephrine.

See also: Xedec II side effects (in more detail)

Levorphanol

Pronunciation: lee-VOR-fa-nole
Generic Name: Levorphanol
Brand Name: Levo-Dromoran

Levorphanol is used for:

Treating or preventing moderate to severe pain. It may also be used before surgery for pain management and for other conditions as determined by your doctor.

Levorphanol is a narcotic analgesic. It works by acting in the brain and spinal cord to decrease the feeling of pain.

Do NOT use Levorphanol if:

• you are allergic to any ingredient in Levorphanol or similar medicines (eg, morphine)


• you are taking a monoamine oxidase (MAO) inhibitor (eg, phenelzine), a narcotic agonist/antagonist medicine (eg, pentazocine), or sodium oxybate (GHB)


• you are having certain types of surgery (eg, biliary surgery)


• you are having an asthma attack, have severe asthma, or have severe diarrhea due to antibiotic use

Contact your doctor or health care provider right away if any of these apply to you.

Video: Treatment for Depression

Treatments for depression are getting better everyday and there are things you can start doing right away.

Before using Levorphanol:

Some medical conditions may interact with Levorphanol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of prostate problems, seizures, heart problems or a recent heart attack, kidney problems, liver disease, an underactive thyroid, severe inflammatory bowel disease, lung problems, asthma, a head injury or increased pressure within the head, a brain tumor, trouble urinating, or low blood pressure


• if you have a history of mental or mood problems or suicidal thoughts


• if you will be having surgery on the stomach, intestines, liver, or gallbladder


• if you consume large amounts of alcohol or have a history of substance abuse or dependence

Some MEDICINES MAY INTERACT with Levorphanol. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Cimetidine, MAO inhibitors (eg, phenelzine), or sodium oxybate (GHB) because side effects of Levorphanol may be increased


• Naltrexone or narcotic agonist/antagonists (eg, pentazocine) because the effectiveness of Levorphanol may be decreased


• Antihistamines (eg, diphenhydramine), barbiturates (eg, phenobarbital), muscle relaxants (eg, methocarbamol), other narcotic pain medicines (eg, codeine), phenothiazines (eg, chlorpromazine), sleeping medicines (eg, zolpidem), or tricyclic antidepressants (eg, amitriptyline) because severe side effects, such as severe drowsiness, low blood pressure, or trouble breathing, may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Levorphanol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Levorphanol:

Use Levorphanol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Levorphanol is usually administered as an injection at your doctor's office, hospital, or clinic. If you are using Levorphanol at home, carefully follow the injection procedures taught to you by your health care provider.


• If Levorphanol contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.


• Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.


• If you miss a dose of Levorphanol and you are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Levorphanol.

Important safety information:

• Levorphanol may cause drowsiness, dizziness, or lightheadedness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Levorphanol. Using Levorphanol alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.


• Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Levorphanol. Levorphanol will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.


• Levorphanol may cause dizziness, lightheadedness, or fainting. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, lightheadedness, or weakness.


• Risk of severe drowsiness, low blood pressure, and severe breathing problems may be increased with high doses or prolonged use. Do NOT exceed the recommended dose or use Levorphanol for longer than prescribed without checking with your doctor.


• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Levorphanol.


• Use Levorphanol with caution in the ELDERLY because they may be more sensitive to its effects.


• Levorphanol is not recommended for use in CHILDREN younger than 18 years of age. Safety and effectiveness in this age group have not been confirmed.


• PREGNANCY and BREAST-FEEDING: It is unknown if Levorphanol can cause harm to the fetus. If you become pregnant while taking Levorphanol, discuss with your doctor the benefits and risks of using Levorphanol during pregnancy. It is unknown if Levorphanol is excreted in breast milk. Do not breast-feed while taking Levorphanol.

When used for long periods of time or at high doses, Levorphanol may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Levorphanol stops working well. Do not take more than prescribed.

When used for long periods of time or at high doses, some people develop a need to continue taking Levorphanol. This is known as DEPENDENCE or addiction.

If you suddenly stop taking Levorphanol, you may experience WITHDRAWAL symptoms, including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing, or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping.

Possible side effects of Levorphanol:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Altered mood and thoughts; constipation; dizziness; drowsiness; flushing; nausea; reaction or pain at the injection site; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); depression; difficulty urinating; fainting; fast, slow, or irregular heartbeat; itching; seizures.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Levorphanol side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include cold and clammy skin; deep sleep; dizziness; drowsiness; lightheadedness; loss of consciousness; slowed breathing; slowed heartbeat.

Proper storage of Levorphanol:

Store at room temperature as directed on the prescription label. Keep Levorphanol out of the reach of children and away from pets.

General information:

• If you have any questions about Levorphanol, please talk with your doctor, pharmacist, or other health care provider.


• Levorphanol is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Levorphanol. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Levorphanol resources

• Levorphanol Side Effects (in more detail)
• Levorphanol Use in Pregnancy & Breastfeeding
• Drug Images
• Levorphanol Drug Interactions
• Levorphanol Support Group
• 5 Reviews for Levorphanol - Add your own review/rating

• Levorphanol Prescribing Information (FDA)


• levorphanol Advanced Consumer (Micromedex) - Includes Dosage Information


• levorphanol Concise Consumer Information (Cerner Multum)


• Levo-Dromoran Monograph (AHFS DI)


• Levo-Dromoran Prescribing Information (FDA)

Compare Levorphanol with other medications

• Light Sedation
• Pain

Antiemetic/antivertigo agents

Vomiting is controlled by the vomiting center in the medulla. Vomiting center is activated by either one of four trigger zones: chemoreceptor trigger zone, vestibular nuclei, cerebral cortex and gastrointestinal tract. Vomiting center is controlled by serotonin (5-HT3), muscarinic and histamine (H1) receptors.

Chemoreceptor trigger zone is sensitive to chemical stimuli, such as opioids and cytotoxic drugs. It is under the control of dopamine, serotonin (5-HT3) and opioid receptors.

Vestibular nuclei is controlled by muscarinic and histamine (H1) receptors. This is activated in vertigo or motion sickness.

Cerebral cortex activates vomiting from smell, thought and so on. Gastrointestinal tract has serotonin (5-HT3) receptors, which are affected by chemotherapeutic drugs.

Different classes of drugs work on different receptors and act as antiemetics and antivertigo agents.

See also

• 5HT3 receptor antagonists
• anticholinergic antiemetics
• miscellaneous antiemetics
• phenothiazine antiemetics

Drug List:

Atenolol

Pronunciation: a-TEN-oh-lol
Generic Name: Atenolol
Brand Name: Tenormin

Do not suddenly stop taking Atenolol. Sharp chest pain, irregular heartbeat, and sometimes heart attack may occur if you suddenly stop Atenolol. The risk may be greater if you have certain types of heart disease. Your doctor should slowly lower your dose over several weeks if you need to stop taking it. This should be done even if you only take Atenolol for high blood pressure. Heart disease is common and you may not know you have it. Limit physical activity while you are lowering your dose. If new or worsened chest pain or other heart problems occur, contact your doctor right away. You may need to start taking Atenolol again.

Atenolol is used for:

Decreasing death due to heart problems after a heart attack. It may also be used for other conditions as determined by your doctor.

Atenolol is a beta-blocker. Exactly how Atenolol works to decrease heart problems after a heart attack is not known.

Do NOT use Atenolol if:

• you are allergic to any ingredient in Atenolol


• you have a very slow heartbeat, heart block, uncontrolled heart failure, shock caused by serious heart problems, or low blood pressure after a heart attack


• you have an untreated adrenal gland tumor (pheochromocytoma)


• you are taking mibefradil

Contact your doctor or health care provider right away if any of these apply to you.

Video: Treatment for Depression

Treatments for depression are getting better everyday and there are things you can start doing right away.

Before using Atenolol:

Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of any severe allergic reaction


• if you have a history of lung or breathing problems (eg, asthma, chronic bronchitis, chronic obstructive pulmonary disease [COPD], emphysema), heart problems (eg, heart failure, conduction problems, left ventricle problems), blood vessel problems, diabetes, kidney problems, an adrenal gland tumor, or an overactive thyroid

Some MEDICINES MAY INTERACT with Atenolol. Tell your health care provider if you are taking any of the following medicines.

• Clonidine because the risk of severe high blood pressure may be increased


• Mefloquine because the risk of irregular heartbeat may be increased


• Amiodarone, calcium channel blockers (eg, diltiazem, verapamil), catecholamine-depleting medicines (eg, reserpine), digoxin, disopyramide, flecainide, ketanserin, mibefradil, or quinidine because they may increase the risk of Atenolol's side effects


• Indomethacin or phenylpropanolamine because it may decrease Atenolol's effectiveness


• Bupivacaine, lidocaine, or quinazolines (eg, alfuzosin) because the risk of their side effects may be increased by Atenolol

This may not be a complete list of all interactions that may occur. Ask your health care provider if Atenolol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Atenolol:

Use Atenolol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Atenolol is usually given as an injection at your doctor's office, hospital, or clinic.


• If you miss a dose of Atenolol, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Atenolol.

Important safety information:

• Atenolol may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Atenolol with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Atenolol may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.


• Tell your doctor or dentist that you take Atenolol before you receive any medical or dental care, emergency care, or surgery.


• Atenolol may reduce the amount of blood that flows to your feet and hands. This may cause them to feel cold and make you more sensitive to the cold. Dress warmly in cold weather. Be careful when you are out in the cold for long periods of time. Ask you doctor for more information.


• If you have a history of any severe allergic reaction, talk with your doctor. You may be at risk for an even more severe allergic reaction if you come into contact with the substance that caused your allergy. Some medicines used to treat severe allergies may also not work as well while you are using Atenolol.


• Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.


• Diabetes patients- Atenolol may hide signs of low blood sugar such as a rapid heartbeat. Other symptoms, such as sweating, may still occur. Check your blood sugar levels regularly. Ask your doctor before you change the dose of your diabetes medicine.


• Check your blood pressure and pulse regularly, as directed by your doctor. Ask your doctor or pharmacist for help if you are unsure how to properly measure your blood pressure or pulse.


• Lifestyle changes may also help reduce your blood pressure. Talk with your doctor about appropriate diet and exercise programs that may be helpful to you.


• Lab tests, including blood pressure and heart function tests, may be performed while you use Atenolol. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Atenolol with caution in the ELDERLY; they may be more sensitive to its effects, especially dizziness.


• Atenolol should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been determined.


• PREGNANCY and BREAST-FEEDING: Atenolol has been shown to cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Atenolol while you are pregnant. Atenolol is found in breast milk. If you are or will be breast-feeding while you use Atenolol, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Atenolol:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome: Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Cold fingers and toes; diarrhea; dizziness; drowsiness; nausea; tiredness or weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blue fingernails, toenails, or palms; decreased sexual ability; fainting; mental or mood problems; persistent dizziness or lightheadedness; shortness of breath; sudden, unusual weight gain; swelling of hands, ankles, or feet; unusual bruising or bleeding; unusually slow heartbeat.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Atenolol side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include breathing problems; chest pain; fainting; pounding in the chest; seizures; severe dizziness; severe weakness; very slow heartbeat; wheezing.

Proper storage of Atenolol:

Atenolol is usually handled and stored by a health care provider. Keep Atenolol, as well as syringes and needles, out of the reach of children and away from pets.

General information:

• If you have any questions about Atenolol, please talk with your doctor, pharmacist, or other health care provider.


• Atenolol is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Atenolol. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Atenolol resources

• Atenolol Side Effects (in more detail)
• Atenolol Use in Pregnancy & Breastfeeding
• Drug Images
• Atenolol Drug Interactions
• Atenolol Support Group
• 58 Reviews for Atenolol - Add your own review/rating

• Atenolol Professional Patient Advice (Wolters Kluwer)


• Atenolol Monograph (AHFS DI)


• atenolol Advanced Consumer (Micromedex) - Includes Dosage Information


• Tenormin Prescribing Information (FDA)


• Tenormin Consumer Overview

Compare Atenolol with other medications

• Alcohol Withdrawal
• Angina
• Angina Pectoris Prophylaxis
• Anxiety
• Esophageal Variceal Hemorrhage Prophylaxis
• Heart Attack
• High Blood Pressure
• Migraine Prevention
• Mitral Valve Prolapse
• Supraventricular Tachycardia
• Ventricular Tachycardia

Akineton HCl

Generic Name: biperiden (bye PEAR i den)

Brand Names: Akineton HCl

What is Akineton HCl (biperiden)?

Biperiden reduces the effects of certain naturally occurring chemicals in your body that may become unbalanced as a result of disease (such as Parkinson's disease), drug therapy, or other causes.

Biperiden is used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease. It is also used to treat and prevent these same muscular conditions when they are caused by drugs such as chlorpromazine (Thorazine), fluphenazine (Prolixin), perphenazine (Trilafon), and others.

Biperiden may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Akineton HCl (biperiden)?

Use caution when driving, operating machinery, or performing other hazardous activities. Biperiden may cause dizziness or blurred vision. If you experience dizziness or blurred vision, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking biperiden.

Avoid becoming overheated. Biperiden may cause decreased sweating. This could lead to heat stroke in hot weather or with vigorous exercise.

Who should not take Akineton HCl (biperiden)?

You cannot take biperiden if you

• 
  

  have ever had an allergic reaction to it,

  
  


• 
  

  have narrow-angle glaucoma,

  
  


• 
  

  have an obstruction in your bowel or a complication of bowel disease known as megacolon; or

  
  


• 
  

  have myasthenia gravis.

  
  

Before taking this medication, tell your doctor if you have

• 
  

  an enlarged prostate or difficulty urinating,

  
  


• 
  

  epilepsy or another seizure disorder,

  
  


• 
  

  heart disease or an irregular heartbeat,

  
  


• 
  

  depression or any other psychiatric illness, or

  
  


• kidney or liver disease.

You may need a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Biperiden is in the FDA pregnancy category C. This means that it is not known whether it will harm an unborn baby. Do not take biperiden without first talking to your doctor if you are pregnant. It is also not known whether biperiden passes into breast milk. Do not take biperiden without first talking to your doctor if you are breast-feeding a baby.

How should I take Akineton HCl (biperiden)?

Take biperiden exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse or doctor to explain them to you.

Take each dose with a full glass of water. Take biperiden after a meal if it upsets your stomach.

Biperiden may be taken once or several times a day. The maximum amount of biperiden that should be taken in any one day is eight tablets (16 mg). Follow your doctor's instructions.

Store biperiden at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and only take your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a biperiden overdose include large pupils; warm, dry skin; flushed face; fever; dry mouth; fast or irregular heartbeat; anxiety; hallucinations; confusion; agitation; hyperactivity; loss of consciousness; and seizures.

What should I avoid while taking Akineton HCl (biperiden)?

Use caution when driving, operating machinery, or performing other hazardous activities. Biperiden may cause dizziness or blurred vision. If you experience dizziness or blurred vision, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking biperiden.

Avoid becoming overheated. Biperiden may cause decreased sweating. This could lead to heat stroke in hot weather or with vigorous exercise. Try to keep as cool as possible and watch for signs of heat stroke such as decreased sweating, nausea, and dizziness.

Akineton HCl (biperiden) side effects

If you experience any of the following serious side effects, stop taking biperiden and seek emergency medical attention:

• 
  

  an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

  
  


• 
  

  unusual fever;

  
  


• 
  

  fast or irregular heartbeat;

  
  


• 
  

  anxiety, hallucinations, confusion, agitation, hyperactivity, or loss of consciousness;

  
  


• 
  

  seizures;

  
  


• 
  

  a rash; or

  
  


• 
  

  eye pain.

  
  

Other, less serious side effects may be more likely to occur. Continue to take biperiden and talk to your doctor if you experience

• 
  

  a dry mouth;

  
  


• 
  

  large pupils or blurred vision;

  
  


• 
  

  drowsiness;

  
  


• 
  

  difficulty urinating or constipation;

  
  


• 
  

  nervousness or anxiety;

  
  


• 
  

  upset stomach; or

  
  


• 
  

  decreased sweating.

  
  

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Akineton HCl (biperiden)?

Before taking this medication, tell your doctor if you are taking:

• a tricyclic antidepressant (TCA) (used to treat depression, pain, or obsessive-compulsive disorder) such as amitriptyline (Elavil, Endep), doxepin (Sinequan), or clomipramine (Anafranil);


• other commonly used tricyclic antidepressants, including amoxapine (Asendin), desipramine (Norpramin), imipramine (Tofranil), nortriptyline (Pamelor), and protriptyline (Vivactil);


• 
  

  a phenothiazine (used to treat mania, schizophrenia, other psychiatric conditions, and nausea and vomiting) such as chlorpromazine (Thorazine), fluphenazine (Prolixin), perphenazine (Trilafon), mesoridazine (Serentil), thioridazine (Mellaril), promazine (Sparine), trifluoperazine (Stelazine), and others;

  
  


• 
  

  an antihistamine such as diphenhydramine (Benadryl, others), chlorpheniramine (Chlor-Trimeton, others), triprolidine (Actifed, others), brompheniramine (Dimetapp, others), clemastine (Tavist) and others (antihistamines are often found in prescription and over-the-counter cold, allergy, and sleep medicines);

  
  


• 
  

  quinidine (Quinora, Quinaglute, Quinidex, Cardioquin);

  
  


• 
  

  amantadine (Symmetrel);

  
  


• 
  

  digoxin (Lanoxin, Lanoxicaps); or

  
  


• 
  

  haloperidol (Haldol).

  
  

Drugs other than those listed here may also interact with biperiden. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

More Akineton HCl resources

• Akineton HCl Side Effects (in more detail)
• Akineton HCl Use in Pregnancy & Breastfeeding
• Drug Images
• Akineton HCl Drug Interactions
• Akineton HCl Support Group
• 0 Reviews for Akineton HCl - Add your own review/rating

• Biperiden Professional Patient Advice (Wolters Kluwer)


• biperiden Advanced Consumer (Micromedex) - Includes Dosage Information


• Biperiden MedFacts Consumer Leaflet (Wolters Kluwer)


• Biperiden Hydrochloride Monograph (AHFS DI)

Compare Akineton HCl with other medications

• Extrapyramidal Reaction
• Parkinson's Disease

Where can I get more information?

• Your pharmacist has more information about biperiden written for health professionals that you may read.

See also: Akineton HCl side effects (in more detail)

Amazapet

Generic Name: inula helenium root, althaea officinalis root, magnesium phosphate, dibasic trihydrate, potassium chloride, arsenic trioxide and phosphorus tablet

Dosage Form: FOR ANIMAL USE ONLY
Amazapet

Relieves bronchospasm and tight chests, plus opens airways

Dosage:  Tablets may be crushed or taken whole.  Cats and dogs under 20 lbs: 1 tablet 3-5 times daily. Dogs 20-50 lbs:  2 tablets 3-5 times daily. Dogs over 50 lbs: 3 tablets 3-5 times daily

Indications: Homeopathic remedy for tight chests, open airways and bronchial health in pets.

Caution:Consult your vet if symptoms persist or worsen

Ingredients:Each dose contains equal parts of Inula (2X) (HPUS), Althea (2X) (HPUS), Mag phos (6X) (HPUS), Kali mur (6X) (HPUS), Arsenicum alb (30C) (HPUS), Phos (30C) (HPUS)

Lactose

Keep this and all medicines from the reach of children.

All Native Remedies health products are especially formulated by experts in the field of natural health and are manufactured according to the highest pharmaceutical standards for maximum safety and effectiveness. For more information, visit us at www.petalive.com

Distributed by

Native Remedies, LLC

6531 Park of Commerce Blvd.  Suite 160

Boca Raton, FL 33487

Phone: +1.877.289.1235

International: +1.561.999.8857

The letters HPUS indicate that the component(s) in this product is (are) officially monographed in the Homeopathic Pharmacopoeia of the United States.

Contains no gluten, artificial flavors, colors or preservatives

Amazapet   inula , althea , mag phos , kali mur, arsenicum alb , phosphorus   tablet

Product Information Product Type OTC ANIMAL DRUG NDC Product Code (Source) 68647-137 Route of Administration ORAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength INULA HELENIUM ROOT (INULA HELENIUM ROOT) INULA HELENIUM ROOT 2 [hp_X] ALTHAEA OFFICINALIS ROOT (ALTHAEA OFFICINALIS ROOT) ALTHAEA OFFICINALIS ROOT 2 [hp_X] MAGNESIUM PHOSPHATE, DIBASIC TRIHYDRATE (MAGNESIUM CATION) MAGNESIUM PHOSPHATE, DIBASIC TRIHYDRATE 6 [hp_X] POTASSIUM CHLORIDE (POTASSIUM CATION) POTASSIUM CHLORIDE 6 [hp_X] ARSENIC TRIOXIDE (ARSENIC TRIOXIDE) ARSENIC TRIOXIDE 30 [hp_C] PHOSPHORUS (PHOSPHATE ION) PHOSPHORUS 30 [hp_C]

Inactive Ingredients Ingredient Name Strength LACTOSE

Product Characteristics Color white (white lactose tablet) Score no score Shape ROUND (round white lactose tablet) Size 5mm Flavor Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 68647-137-10 125 TABLET In 1 BOTTLE, GLASS None

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
unapproved homeopathic		01/01/2010

Labeler - Feelgood Health (538418296)

Establishment
Name	Address	ID/FEI	Operations
W Last		567284153	manufacture

Revised: 09/2010Feelgood Health

Kapvay Extended-Release Tablets

Pronunciation: KLOE-ni-deen
Generic Name: Clonidine
Brand Name: Kapvay

Kapvay Extended-Release Tablets are used for:

Treating attention deficit hyperactivity disorder (ADHD). It may be used alone or with other medicines. Kapvay Extended-Release Tablets should be used as part of an ADHD treatment program that includes a variety of treatment measures (eg, psychological, educational, social). It may also be used for other conditions as determined by your doctor.

Kapvay Extended-Release Tablets are an alpha-2 receptor agonist. Exactly how it works to treat ADHD is not known.

Do NOT use Kapvay Extended-Release Tablets if:

• you are allergic to any ingredient in Kapvay Extended-Release Tablets


• you are taking another medicine that contains clonidine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Kapvay Extended-Release Tablets:

Some medical conditions may interact with Kapvay Extended-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have had a skin reaction to the patch form of Kapvay Extended-Release Tablets


• if you have kidney problems, problems with the blood vessels in your heart or brain, or the blood disease porphyria; you are dehydrated; or you will be having surgery


• if you have a history of a stroke; a recent heart attack; low blood pressure; dizziness or fainting; or fast, slow, or irregular heartbeat or other heart problems (eg, heart block)


• if you are taking a medicine for high blood pressure

Some MEDICINES MAY INTERACT with Kapvay Extended-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Barbiturates (eg, phenobarbital), benzodiazepines (eg, alprazolam), beta-blockers (eg, propranolol), calcium channel blockers (eg, verapamil), digoxin, or phenothiazines (eg, chlorpromazine) because they may increase the risk of Kapvay Extended-Release Tablets's side effects


• Tricyclic antidepressants (eg, amitriptyline) because they may decrease Kapvay Extended-Release Tablets's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Kapvay Extended-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Kapvay Extended-Release Tablets:

Use Kapvay Extended-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Kapvay Extended-Release Tablets. Talk to your pharmacist if you have questions about this information.


• Swallow Kapvay Extended-Release Tablets whole. Do not break, crush, or chew before swallowing.


• Take Kapvay Extended-Release Tablets by mouth with or without food.


• Take Kapvay Extended-Release Tablets on a regular schedule to get the most benefit from it.


• Continue to take Kapvay Extended-Release Tablets even if you feel well. Do not miss any doses.


• If you miss a dose of Kapvay Extended-Release Tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Kapvay Extended-Release Tablets.

Important safety information:

• Kapvay Extended-Release Tablets may cause drowsiness, dizziness, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Kapvay Extended-Release Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Kapvay Extended-Release Tablets may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects. Avoid becoming dehydrated or overheated.


• Do not drink alcohol while you are using Kapvay Extended-Release Tablets. Talk to your doctor before using medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Kapvay Extended-Release Tablets; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.


• Do not switch between types of Kapvay Extended-Release Tablets without checking with your doctor. Different types may not work the same way in your body.


• Tell your doctor or dentist that you take Kapvay Extended-Release Tablets before you receive any medical or dental care, emergency care, or surgery.


• Do not suddenly stop taking Kapvay Extended-Release Tablets without talking to your doctor. Side effects may occur, including nervousness, agitation, confusion, tremor, and headache. These may be followed by a rapid, severe rise in blood pressure. If you need to stop taking Kapvay Extended-Release Tablets, follow your doctor's instructions for slowly decreasing your dose.


• Talk with your doctor if you will be using Kapvay Extended-Release Tablets long-term (more than 5 weeks). Your doctor may periodically evaluate your condition if you will be using Kapvay Extended-Release Tablets long-term.


• Lab tests, including blood pressure and heart rate, may be performed while you take Kapvay Extended-Release Tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Kapvay Extended-Release Tablets should be used with extreme caution in ADULTS; safety and effectiveness in adults have not been confirmed.


• Kapvay Extended-Release Tablets should be used with extreme caution in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Kapvay Extended-Release Tablets while you are pregnant. Kapvay Extended-Release Tablets are found in breast milk. If you are or will be breast-feeding while you use Kapvay Extended-Release Tablets, check with your doctor. Discuss any possible risks to your baby.

If you stop taking Kapvay Extended-Release Tablets suddenly, you may have WITHDRAWAL symptoms. These may include nervousness, agitation, anxiety, headache, tremor, flushing, fast heartbeat, nausea, lightheadedness, warm feeling, chest tightness, and rapid increase in blood pressure. Do not suddenly stop taking Kapvay Extended-Release Tablets without checking with your doctor.

Possible side effects of Kapvay Extended-Release Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; drowsiness; dry mouth; headache; increased thirst; nausea; stuffy or runny nose; tiredness; trouble sleeping.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); ear or throat pain; fainting; fast, slow, or irregular heartbeat; fever, chills, or sore throat; mental or mood changes (eg, aggression, anxiety, irritability); nightmares; nosebleeds; severe or persistent headache, drowsiness, or dizziness; shortness of breath or wheezing; stomach pain; tremor; urinary problems (eg, frequent urination, uncontrolled bladder).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Kapvay side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include coma; decreased body temperature (feeling very cold); decreased or absent reflexes; difficult or slow breathing; fainting; irritability; pinpoint pupils; seizures; severe or persistent headache, dizziness, or drowsiness; slow or irregular heartbeat; weakness.

Proper storage of Kapvay Extended-Release Tablets:

Store Kapvay Extended-Release Tablets at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Do not store in the bathroom. Store away from heat, moisture, and light. Keep Kapvay Extended-Release Tablets out of the reach of children and away from pets.

General information:

• If you have any questions about Kapvay Extended-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.


• Kapvay Extended-Release Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Kapvay Extended-Release Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Kapvay resources

• Kapvay Side Effects (in more detail)
• Kapvay Dosage
• Kapvay Use in Pregnancy & Breastfeeding
• Kapvay Drug Interactions
• Kapvay Support Group
• 11 Reviews for Kapvay - Add your own review/rating

Compare Kapvay with other medications

• ADHD