Sunday, 18 March 2012

mupirocin nasal


Generic Name: mupirocin nasal (mue PIR oh sin)

Brand Names: Bactroban


What is mupirocin nasal?

Mupirocin is an antibiotic that treats or prevents infection caused by bacteria.


Mupirocin nasal (for the nose) is used to prevent severe staph infections in patients and healthcare workers who may be at risk of infection during an outbreak within a hospital or other healthcare setting.


Mupirocin nasal may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about mupirocin nasal?


Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the instructions on your prescription label.


Mupirocin nasal is usually given for 5 days. To best protect you from infection, use this medication for the entire length of time prescribed by your doctor. Mupirocin nasal will not treat or prevent a viral infection such as the common cold or flu. Stop using mupirocin nasal and call your doctor at once if you have severe burning or stinging of your nose or eyes.

Do not use other nasal medications at the same time you apply mupirocin nasal.


What should I discuss with my health care provider before taking mupirocin nasal?


You should not use this medication if you are allergic to mupirocin. FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether mupirocin nasal passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Mupirocin nasal should not be used in a child younger than 12 years old.

How should I take mupirocin nasal?


Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the instructions on your prescription label.


Mupirocin nasal ointment is packaged in single-use tubes. Use one half of the medicine from the tube in your left nostril, and use the other half in your right nostril. After placing the ointment into your nostrils, gently press your nostrils closed and then release them, repeating for about 1 minute to help spread the ointment inside your nose.


Throw the ointment tube away after one use, even if there is still some ointment left in it.


Mupirocin nasal is usually given for 5 days. To best protect you from infection, use this medication for the entire length of time prescribed by your doctor. Mupirocin nasal will not treat or prevent a viral infection such as the common cold or flu. Store mupirocin nasal at room temperature away from moisture and heat. Do not refrigerate.

What happens if I miss a dose?


Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and use the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of mupirocin nasal is not expected to produce life-threatening symptoms.


What should I avoid while taking mupirocin nasal?


Avoid getting this medication in your eyes. If this does happen, rinse with water.

Do not use other nasal medications at the same time you apply mupirocin nasal.


Mupirocin nasal side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using mupirocin nasal and call your doctor at once if you have any of these serious side effects:

  • severe burning or stinging of your nose;




  • nosebleed; or




  • severe burning or watering of your eyes.



Less serious side effects may include:



  • dryness or unpleasant taste in your mouth;




  • headache;




  • ear pain;




  • runny or stuffy nose;




  • nausea, diarrhea;




  • itching, mild skin rash;




  • cough; or




  • sore throat.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Mupirocin nasal Dosing Information


Usual Adult Dose for Skin and Structure Infection:

Cream:
A small amount applied to the affected area 3 times a day for 10 days.

Ointment:
A small amount applied to the affected area 3 times a day for 7 to 14 days.

Usual Adult Dose for Nasal Carriage of Staphylococcus aureus:

Divide 1/2 of the ointment from the single-use tube between the nostrils and apply twice daily for 5 days.

Usual Pediatric Dose for Skin and Structure Infection:

Cream:
3 months to 16 years:
A small amount applied to the affected area 3 times a day for 10 days.

Ointment:
2 months to 16 years:
A small amount applied to the affected area 3 times a day for 7 to 14 days.

Usual Pediatric Dose for Nasal Carriage of Staphylococcus aureus:

Greater than or equal to 12 years:
Divide 1/2 of the ointment from the single-use tube between the nostrils and apply twice daily for 5 days.


What other drugs will affect mupirocin nasal?


There may be other drugs that can interact with mupirocin nasal. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.



More mupirocin nasal resources


  • Mupirocin nasal Side Effects (in more detail)
  • Mupirocin nasal Use in Pregnancy & Breastfeeding
  • Mupirocin nasal Support Group
  • 13 Reviews for Mupirocin - Add your own review/rating


Compare mupirocin nasal with other medications


  • Nasal Carriage of Staphylococcus aureus
  • Skin and Structure Infection


Where can I get more information?


  • Your pharmacist can provide more information about mupirocin nasal.

See also: mupirocin side effects (in more detail)


Ergomar


Generic Name: ergotamine (er GOT a meen)

Brand Names: Ergomar


What is Ergomar (ergotamine)?

Ergotamine is in a group of drugs called ergot alkaloids (ER-got AL-ka-loids). It works by narrowing the blood vessels around the brain. Ergotamine also affects blood flow patterns that are associated with certain types of headaches.


Ergotamine is used to treat a migraine type headache.


This medication will only treat a headache that has already begun. It will not prevent migraine headaches or reduce the number of attacks.


Ergotamine should not be used to treat common tension headaches or any headache that seems to be different from your usual migraine headaches.

Ergotamine may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Ergomar (ergotamine)?


This medication can harm an unborn baby or a nursing baby. Do not take ergotamine if you are pregnant or breast-feeding. Do not take this medication if you are allergic to ergotamine or other ergot medicines, or if you have a history of heart disease, angina (chest pain), blood circulation problems, history of a heart attack or stroke, coronary artery disease, uncontrolled high blood pressure, severe liver or kidney disease, or a serious infection. Using certain medications together with ergotamine can cause even greater decreases in blood flow than ergotamine used alone, which can lead to dangerous side effects. Tell your doctor about all other medications you are using.

Also tell your doctor about all of your medical conditions, especially high blood pressure, liver or kidney disease, or risk factors for coronary artery disease (diabetes, high blood pressure or cholesterol, menopause or hysterectomy, smoking, taking birth control pills, being overweight, having a family history of coronary artery disease, or being a man older than 40).


This medication will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.


Never take more than your prescribed dose of ergotamine. An overdose can be fatal.

What should I discuss with my healthcare provider before taking Ergomar (ergotamine)?


Do not take this medication if you are allergic to ergotamine or similar medications such as Cafergot, D.H.E. 45, Migergot, Migranal, or Methergine.

Do not take ergotamine if you are pregnant or breast-feeding, or if you have:



  • a history of heart disease, angina (chest pain), blood circulation problems, or history of a heart attack or stroke;




  • coronary artery disease or "hardening of the arteries";




  • uncontrolled high blood pressure;



  • severe liver disease;

  • severe kidney disease; or


  • a serious infection called sepsis.




Using certain medications together with ergotamine can cause even greater decreases in blood flow than ergotamine used alone, which can lead to dangerous side effects. Do not take ergotamine if you are also using any of the following medications:

  • conivaptan (Vaprisol), imatinib (Gleevec), isoniazid (for treating tuberculosis), or nefazodone (an antidepressant);




  • diclofenac (Arthrotec, Cataflam, Voltaren, Flector Patch, Solareze);




  • clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), or telithromycin (Ketek);




  • clotrimazole (Mycelex Troche), itraconazole (Sporanox), ketoconazole (Extina, Ketozole, Nizoral, Xolegal), or voriconazole (Vfend);




  • heart or blood pressure medication such as diltiazem (Cardizem, Dilacor, Tiazac), nicardipine (Cardene), quinidine (Quin-G), or verapamil (Calan, Covera, Isoptin, Verelan); or




  • HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), saquinavir (Invirase, Fortovase), or ritonavir (Norvir).



Ergotamine can cause rare but serious side effects on the heart, including heart attack or stroke. To make sure you can safely take ergotamine, tell your doctor if you have any of these other conditions:



  • high blood pressure;




  • liver disease;




  • kidney disease; or




  • coronary artery disease (or risk factors that include diabetes, menopause, smoking, being overweight, having high blood pressure or high cholesterol, having a family history of coronary artery disease, being older than 40 and a man, or being a woman who has had a hysterectomy).




FDA pregnancy category X. Ergotamine can cause birth defects. Do not use if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Use an effective form of birth control while you are using this medication. Ergotamine can pass into breast milk and may harm a nursing baby. Ergotamine may also decrease milk production. Do not use if you are breast-feeding a baby.

How should I take Ergomar (ergotamine)?


Take exactly as prescribed by your doctor. Never take more than your prescribed dose of ergotamine. Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in treating your migraine attacks. Ergotamine is not for daily use.


Take the first dose of ergotamine as soon as you notice headache symptoms, or after an attack has already begun. Place 1 ergotamine tablet under your tongue.


If your headache does not completely go away, you may take a second tablet after at least 30 minutes have passed, and a third tablet if needed after another 30 minutes have passed (a total of 3 tablets).


If you still have migraine symptoms after taking a total of 3 tablets, call your doctor. Do not take more than a total of 3 tablets in any 24-hour period. Do not take more than a total of 5 tablets over a period of 7 days. Do not give this medication to anyone else, even if they have the same headache symptoms you have. Ergotamine can be dangerous if it is used to treat headache in a person who has not been diagnosed by a doctor as having true migraine headaches. Store at room temperature away from moisture, heat, and light. Do not take any stored ergotamine if the expiration date on the label has passed.

What happens if I miss a dose?


Since ergotamine is taken only when needed, you are not likely to miss a dose.


Do not take more than 3 ergotamine tablets per day or more than 5 tablets per week.

What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of ergotamine can be fatal.

Overdose can cause vomiting, confusion, drowsiness, weak pulses in your arms and legs, numbness and tingling or pain in your hands or feet, blue-colored fingers or toes, fainting, and seizure (convulsions).


What should I avoid while taking Ergomar (ergotamine)?


Do not take ergotamine within 24 hours before or after using another migraine headache medicine, including:

  • dihydroergotamine (D.H.E. 45, Migranal), caffeine and ergotamine (Cafergot, Ercaf, Wigraine), ergonovine (Ergotrate), methylergonovine (Methergine), methysergide (Sansert); or




  • almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), sumatriptan (Imitrex), rizatriptan (Maxalt, Maxalt-MLT), or zolmitriptan (Zomig).



Grapefruit and grapefruit juice may interact with ergotamine and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.


Ergomar (ergotamine) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking ergotamine and call your doctor at once if you have a serious side effect such as:

  • sudden numbness or weakness, especially on one side of the body;




  • sudden headache, confusion, problems with vision, speech, or balance;




  • fast or slow heart rate;




  • muscle pain in your arms or legs;




  • leg weakness;




  • numbness or tingling and a pale or blue-colored appearance in your fingers or toes;




  • severe pain in your stomach or lower back;




  • urinating less than usual or not at all;




  • swelling or itching in any part of your body;




  • cough with stabbing chest pain and trouble breathing; or




  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).



Less serious side effects may include:



  • dizziness, spinning sensation;




  • weakness;




  • nausea, vomiting; or




  • mild itching.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Ergomar (ergotamine)?


Many drugs can interact with ergotamine. Below is just a partial list. Talk with your doctor before taking ergotamine if you are also taking:



  • birth control pills;




  • zileuton (Zyflo);




  • cold or allergy medications;




  • nicotine (Nicoderm, Nicorette);




  • diet pills, stimulants, or medication to treat ADHD (such as Ritalin or Adderall);




  • an antidepressant such as fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), nefazodone (Serzone), paroxetine (Paxil), sertraline (Zoloft), and others;




  • an antibiotic such as metronidazole (Flagyl);




  • clotrimazole (Mycelex Troche), fluconazole (Diflucan), or other antifungal medication;




  • nitroglycerin or other nitrate medicines such as isosorbide (Isordil, Dilatrate, Imdur, Monoket); or




  • heart or blood pressure medication such as atenolol (Tenormin), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others.



This list is not complete and other drugs may interact with ergotamine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Ergomar resources


  • Ergomar Side Effects (in more detail)
  • Ergomar Use in Pregnancy & Breastfeeding
  • Ergomar Drug Interactions
  • Ergomar Support Group
  • 1 Review for Ergomar - Add your own review/rating


  • Ergomar Monograph (AHFS DI)

  • Ergomar MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Ergomar with other medications


  • Migraine


Where can I get more information?


  • Your pharmacist can provide more information about ergotamine.

See also: Ergomar side effects (in more detail)


Saturday, 17 March 2012

Allfen CX Sustained-Release Tablets


Pronunciation: car-bay-ta-PEN-tane/gwye-FEN-e-sin
Generic Name: Carbetapentane/Guaifenesin
Brand Name: Examples include Allfen CX and Xpect-AT


Allfen CX Sustained-Release Tablets are used for:

Relieving unproductive cough and reducing mucus in the chest due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.


Allfen CX Sustained-Release Tablets are a cough suppressant and expectorant combination. The cough suppressant works in the brain to help decrease the cough reflex. The expectorant works by thinning mucus (phlegm) in the lungs, making it less sticky and easier to cough up. This makes coughs more productive.


Do NOT use Allfen CX Sustained-Release Tablets if:


  • you are allergic to any ingredient in Allfen CX Sustained-Release Tablets

  • the patient is a newborn or infant

  • you have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the past 14 days

Contact your doctor or health care provider right away if any of these apply to you.



Before using Allfen CX Sustained-Release Tablets:


Some medical conditions may interact with Allfen CX Sustained-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have chronic cough due to smoking, asthma, chronic bronchitis, or emphysema, or if your cough produces large amounts of mucus

  • if you have a history of heart or blood vessel problems, high blood pressure, prostate problems, an overactive thyroid, diabetes, or glaucoma

Some MEDICINES MAY INTERACT with Allfen CX Sustained-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • MAOIs (eg, phenelzine) because the risk of their side effects may be increased by Allfen CX Sustained-Release Tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Allfen CX Sustained-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Allfen CX Sustained-Release Tablets:


Use Allfen CX Sustained-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Allfen CX Sustained-Release Tablets by mouth with or without food.

  • Drinking extra fluids while you are taking Allfen CX Sustained-Release Tablets are recommended. Check with your doctor for instructions.

  • Swallow Allfen CX Sustained-Release Tablets whole. Do not break, crush, or chew before swallowing. Some brands of Allfen CX Sustained-Release Tablets may be broken in half before taking. If you have difficulty swallowing the whole tablet, ask your pharmacist if your brand of medicine may be broken in half.

  • If you miss a dose of Allfen CX Sustained-Release Tablets and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Allfen CX Sustained-Release Tablets.



Important safety information:


  • Allfen CX Sustained-Release Tablets may cause drowsiness. This effect may be worse if you take it with alcohol or certain medicines. Use Allfen CX Sustained-Release Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Allfen CX Sustained-Release Tablets; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

  • Do not use Allfen CX Sustained-Release Tablets for a cough with a lot of mucous. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.

  • If cough persists for more than 1 week or is accompanied by a fever, contact your health care provider. A persistent cough could be a sign of a serious condition.

  • Allfen CX Sustained-Release Tablets should not be used in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Allfen CX Sustained-Release Tablets while you are pregnant. It is not known if Allfen CX Sustained-Release Tablets are found in breast milk. If you are or will be breast-feeding while you take Allfen CX Sustained-Release Tablets, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Allfen CX Sustained-Release Tablets:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Drowsiness; dry mouth, nose, or throat; upset stomach.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Allfen CX side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include restlessness; seizures; severe agitation.


Proper storage of Allfen CX Sustained-Release Tablets:

Store Allfen CX Sustained-Release Tablets between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Allfen CX Sustained-Release Tablets out of the reach of children and away from pets.


General information:


  • If you have any questions about Allfen CX Sustained-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.

  • Allfen CX Sustained-Release Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Allfen CX Sustained-Release Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Allfen CX resources


  • Allfen CX Side Effects (in more detail)
  • Allfen CX Use in Pregnancy & Breastfeeding
  • Allfen CX Drug Interactions
  • Allfen CX Support Group
  • 0 Reviews for Allfen CX - Add your own review/rating


Compare Allfen CX with other medications


  • Cough

Friday, 16 March 2012

Asenapine


Pronunciation: a-SEN-a-peen
Generic Name: Asenapine
Brand Name: Saphris

Asenapine is an antipsychotic. It may increase the risk of death when used to treat mental problems caused by dementia in elderly patients. Most of the deaths were linked to heart problems or infection. Asenapine is not approved to treat mental problems caused by dementia. Discuss any questions or concerns with your doctor.





Asenapine is used for:

Treating schizophrenia. It is used alone or along with lithium or valproate to treat acute manic or mixed episodes associated with bipolar disorder (manic-depression). It may also be used for other conditions as determined by your doctor.


Asenapine is an atypical antipsychotic. Exactly how it works is not known. It may work by blocking certain substances in the brain.


Do NOT use Asenapine if:


  • you are allergic to any ingredient in Asenapine

  • you have severe liver problems, low blood potassium or magnesium levels, slow heartbeat, or a history of irregular heartbeat (eg, long QT syndrome, congenital prolongation of the QT interval)

  • you are taking an antiarrhythmic (eg, amiodarone, sotalol, procainamide, quinidine), certain other antipsychotic medicines (eg, ziprasidone, chlorpromazine, thioridazine), a phenothiazine (eg, thioridazine), or a quinolone antibiotic (eg, gatifloxacin, moxifloxacin)

  • if you take any medicine that may increase the risk of a certain type of irregular heartbeat (prolonged QT interval). Check with your doctor or pharmacist if you are unsure if any of your medicines may increase the risk of this type of irregular heartbeat

Contact your doctor or health care provider right away if any of these apply to you.



Before using Asenapine:


Some medical conditions may interact with Asenapine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have diabetes or are at risk of diabetes (eg, overweight, family history of diabetes)

  • if you have a history of heart problems (eg, fast, slow, or irregular heartbeat; heart failure; ischemic heart disease), a heart attack, low blood pressure, blood vessel problems, a stroke, or low white blood cell levels

  • if you have a history of liver problems, neuroleptic malignant syndrome (NMS), seizures, suicidal thoughts or attempts, or alcohol abuse or dependence

  • if you have Alzheimer disease, dementia, Parkinson disease, or esophagus problems (eg, trouble swallowing)

  • if you are dehydrated, have a low blood volume, drink alcohol, or will be exposed to very high or very low temperatures

  • if you have had high blood prolactin levels or a history of certain types of cancer (eg, breast, pancreas, pituitary, brain), or if you are at risk of breast cancer

  • if you are taking a medicine to treat high blood pressure

  • if you have never taken an antipsychotic medicine before. You may be more likely to experience dizziness when you sit or stand up

Some MEDICINES MAY INTERACT with Asenapine. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Antiarrhythmics (eg, amiodarone, procainamide, quinidine, sotalol), other antipsychotic medicines (eg, ziprasidone, chlorpromazine, thioridazine), phenothiazines (eg, thioridazine), quinolone antibiotics (eg, gatifloxacin, moxifloxacin) because the risk of irregular heartbeat may be increased

  • Fluvoxamine because it may increase the risk of Asenapine's side effects

  • Anticholinergics (eg, scopolamine) or paroxetine because the risk of their side effects may be increased by Asenapine

This may not be a complete list of all interactions that may occur. Ask your health care provider if Asenapine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Asenapine:


Use Asenapine as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Wash and completely dry your hands before you take Asenapine. Do not handle the tablet with wet or damp hands.

  • Do not remove the tablet from the tablet pack until you are ready to take Asenapine. Take the tablet immediately after opening the blister pack. Do not store the removed tablet for future use.

  • To remove Asenapine from the tablet pack, firmly press and hold the thumb button, then pull out the tablet pack. Peel back the colored tab and gently remove the tablet. Do not push the tablet through the tablet pack. Do not cut or tear the tablet pack.

  • Do not swallow, crush, or chew sublingual tablets. Place the tablet under your tongue and allow it to completely dissolve. Do not eat, drink, or smoke while the tablet is dissolving.

  • Do not eat or drink anything for 10 minutes after you take Asenapine.

  • After you have taken your dose, slide the tablet pack into the case until it clicks.

  • Taking Asenapine at the same time each day will help you remember to take it.

  • Take Asenapine on a regular schedule to get the most benefit from it.

  • Continue to take Asenapine even if you feel well. Do not miss any doses.

  • If you miss a dose of Asenapine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Asenapine.



Important safety information:


  • Asenapine may cause drowsiness, dizziness, or light-headedness. These effects may be worse if you take it with alcohol or certain medicines. Use Asenapine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Do not drink alcohol while you are taking Asenapine.

  • Talk with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are taking Asenapine; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

  • Asenapine may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

  • Do not suddenly stop taking Asenapine without checking with your doctor.

  • Do not become overheated or dehydrated in hot weather or while you are being active; heatstroke may occur.

  • If vomiting or diarrhea occurs, you will need to take care not to become dehydrated. Contact your doctor for instructions. Contact your doctor right away if you think you may be dehydrated.

  • Asenapine may increase your risk for developing diabetes or increase blood sugar levels. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.

  • Diabetes patients - Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.

  • Asenapine may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.

  • Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome that can be caused by Asenapine. Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your doctor at once if you have any of these symptoms.

  • Some patients who take Asenapine may develop muscle movements that they cannot control. This is more likely to happen in elderly patients, especially women. The chance that this will happen or that it will become permanent is greater in those who take Asenapine in higher doses or for a long time. Muscle problems may also occur after short-term treatment with low doses. Tell your doctor at once if you have muscle problems with your arms; legs; or your tongue, face, mouth, or jaw (eg, tongue sticking out, puffing of cheeks, mouth puckering, chewing movements) while taking Asenapine.

  • Asenapine may increase the amount of a certain hormone (prolactin) in your blood. Symptoms may include enlarged breasts, missed menstrual period, decreased sexual ability, or nipple discharge. Contact your doctor right away if you experience any of these symptoms.

  • Lab tests, including complete blood cell counts, electrolyte levels, weight checks, or fasting blood sugar levels, may be performed while you use Asenapine. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Asenapine with caution in the ELDERLY; they may be more sensitive to its effects, especially uncontrolled muscle movements or dizziness when sitting or standing up.

  • Asenapine should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking Asenapine while you are pregnant. Using Asenapine during the third trimester may result in uncontrolled muscle movements or withdrawal symptoms in the newborn. Discuss any questions or concerns with your doctor. It is not known if Asenapine is found in breast milk. Do not breast-feed while taking Asenapine.


Possible side effects of Asenapine:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Decreased feeling around the mouth; dizziness; drowsiness; dry mouth; headache; increased appetite; increased saliva production; indigestion; joint aches; restlessness; taste changes; tiredness; trouble sleeping; upset stomach; vomiting; weight gain.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness; wheezing); change in the amount of urine produced; chest pain; fainting or loss of consciousness; fast, slow, or irregular heartbeat; fever, chills, or persistent sore throat; muscle pain, weakness, or stiffness; new or worsening mental or mood changes (eg, aggression, agitation, depression, severe anxiety); seizures; severe or persistent dizziness or light-headedness; shortness of breath; suicidal thoughts or actions; symptoms of high blood sugar (eg, increased thirst, hunger, or urination; confusion; flushing; rapid breathing; fruit-like breath odor; weakness); symptoms of high prolactin levels (eg, enlarged breast size, decreased sexual ability, missed menstrual period, nipple discharge); trouble swallowing; uncontrolled muscle movements (eg, of the arms, legs, tongue, jaw, or cheeks; tremors; twitching); unusual sweating.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Asenapine side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include agitation; confusion; fainting; severe dizziness; uncontrolled muscle movements.


Proper storage of Asenapine:

Store Asenapine at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Asenapine out of the reach of children and away from pets.


General information:


  • If you have any questions about Asenapine, please talk with your doctor, pharmacist, or other health care provider.

  • Asenapine is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Asenapine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Asenapine resources


  • Asenapine Side Effects (in more detail)
  • Asenapine Use in Pregnancy & Breastfeeding
  • Asenapine Drug Interactions
  • Asenapine Support Group
  • 89 Reviews for Asenapine - Add your own review/rating


  • Asenapine Professional Patient Advice (Wolters Kluwer)

  • asenapine Sublingual Advanced Consumer (Micromedex) - Includes Dosage Information

  • Asenapine Maleate Monograph (AHFS DI)

  • Saphris Prescribing Information (FDA)

  • Saphris Consumer Overview



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Wednesday, 14 March 2012

Nuelin SA Tablets





Nuelin SA Tablets




What you need to know about NUELIN SA tablets


Please read this carefully before you start to use your medication. This leaflet only provides a summary of the information available on your medication. If you have any questions or are not sure about anything ask your doctor or pharmacist.




The name of your medication is NUELIN SA tablets



Nuelin SA tablets contain an active ingredient called theophylline which is a bronchodilator. There are two strengths available, 175 mg or 250 mg. The 175 mg tablets are white, round and marked NLS 175 on one side and 3M on the other. The 250 mg tablets are white, round and marked NLS 250 on one side and 3M on the other.


The tablets also contain the following inactive ingredients: lactose, cellulose acetate phthalate, magnesium stearate. Each original pack contains 60 tablets.





Who produces your medication


The name and address of the product licence holder is



Meda Pharmaceuticals Ltd

Skyway House

Parsonage Road

Takeley

Bishop’s Stortford

CM22 6PU

UK


The product is manufactured by



3M Health Care Limited

Loughborough

Leicestershire

LE11 1EP




What your medication is prescribed for


Theophylline is a bronchodilator which widens the air passages of the lungs and makes breathing easier.


Theophylline can help you feel less tight chested, less breathless or less wheezy. Your doctor may prescribe these tablets for asthma or the relief of wheezing and shortness of breath caused by some other chest diseases.



Important points to note before taking NUELIN SA tablets



If you are pregnant, think you might be pregnant, or are trying to become pregnant, or are taking other medications, please tell your doctor before taking these tablets.


These tablets should not be taken if you are allergic to theophylline or aminophylline.


Please tell your doctor if you are suffering from any of the following:cardiac arrhythmias (irregular heart beat), heart failure, liver disease, a peptic (stomach) ulcer, an overactive thyroid gland, high blood pressure, porphyria, alcoholism, lung disease, severe asthma or fever.


If you suffer from epilepsy (fits), you should consult your doctor for an alternative bronchodilator.


If you drink alcohol or smoke, please tell your doctor.


These tablets should not be taken by children under 6 years of age.


If you see any other doctor or dentist, please tell them that you are taking Nuelin SA tablets.





What to do if you are taking other medication


If you are taking any of the following, please tell your doctor:aminophylline or theophylline, steroids, diuretics (water tablets), bronchodilators (drugs for relieving asthma), oral contraceptives, barbituratesor antibiotics, ß-blockers (used to treat high blood pressure or angina), doxapram and ketamine.


Please tell your doctor if you are taking any of the following medicines: cimetidine, allopurinol, isoprenaline, thiabendazole, ciprofloxacin, erythromycin, phenytoin, carbamazepine, lithium, rifampicin, frusemide, sulphinpyrazone, fluvoxamine, diltiazem, verapamil, nizatidine, norfloxacin, isoniazid, fluconazole, carbimazole, mexiletine, propafenone, oxpentifylline, disulfiram, ritonavir, aminoglutethimide, viloxazine, primidone, interferon alfa, and influenza vaccine.


The herbal remedy St John’s wort (Hypericum perforatum) should not be taken at the same time as this medicine. If you already take St John’s wort, consult your doctor before stopping the St John’s wort preparation.



The taking of NUELIN SA tablets during pregnancy and breast feeding


Like other medication, theophylline should not be taken if you are pregnant, unless your doctor tells you to. If you are breast feeding, please consult your doctor before taking these tablets.





How to take NUELIN SA tablets


Please follow your doctor’s instructions.



Nuelin SA tablets should be taken after food. These tablets should be swallowed whole and not crushed or chewed.



NUELIN SA 175 mg tablets


The usual dose of these tablets for adults is one tablet twice daily. This may be increased to two tablets twice daily.


If you are elderly your doctor may prescribe a lower dose for you.


The usual dose for children (6-12 years) is one tablet twice daily.




NUELIN SA 250 mg tablets


The usual dose of these tablets for adults is one tablet twice daily. This may be increased to two tablets twice daily.


If you are elderly your doctor may prescribe a lower dose for you.


The usual dose for children (6-12 years) is half or one tablet twice daily.



Nuelin SA 250 mg tablets may be cut in half, but they should not be crushed or chewed.



If you miss a dose, take it as soon as you remember. Then carry on taking the tablets as recommended by your doctor.


If you are not sure how many tablets to take or how often to take them please ask your doctor or pharmacist.




What to do if an accidental overdose is taken


Please contact your nearest hospital casualty department, or tell your doctor, immediately.



What might happen when you are taking NUELIN SA tablets


Like other medications, theophylline may cause some side-effects.


These may include stomach upset, palpitations (fast heart beat), headache, feeling sick, sleeplessness, restlessness, excitability, irritability or anxiety.


If you notice any other side-effects, please tell your doctor or pharmacist.


If any of these side-effects continue for more than a few days, please tell your doctor or pharmacist.


Your doctor may wish to test your blood to check your potassium balance from time to time, whilst you are taking these tablets. He/she may also use blood tests to make sure that you are receiving the correct dose of theophylline.





Storing your medication


Store the tablets in a safe place where children cannot reach them.


Store the tablets below 30°C. Do not use after the expiry date printed on the original container.


If your doctor decides to stop treatment, return any unused tablets to your pharmacist.



Date of preparation of leaflet: February 2010.



REMEMBER: This medication is only for YOU. Never give it to others. It may harm them even if their illness seems to be the same as yours.


The information in this leaflet provides a summary of the information available on Nuelin SA tablets.


Further information is available from your doctor or pharmacist.



6204 0230 1


562197M5110UK00


Nuelin is a trademark of MEDA AB.


The Triangle Logo on the packaging is a trademark of 3M and is used under license.





Thursday, 8 March 2012

Vansil


Generic Name: oxamniquine (ox AM ni kwin)

Brand Names: Vansil


What is Vansil (oxamniquine)?

Oxamniquine is an "antihelmintic," or anti-worm, medication. It prevents worms from growing or multiplying in your body.


Oxamniquine is used only to treat infections caused by the worm Schistosoma mansoni. This is an uncommon infection usually acquired through contact with freshwater in Africa.


Oxamniquine is not commercially available in the United States.


Oxamniquine may also be used for purposes other than those listed in this medication guide.


What is the most important information I should know about Vansil (oxamniquine)?


Oxamniquine is not commercially available in the United States.


Use caution when driving, operating machinery, or performing other hazardous activities. Oxamniquine may cause dizziness. If you experience dizziness, avoid these activities. Take oxamniquine with food to lessen stomach upset.

Who should not take Vansil (oxamniquine)?


Before taking oxamniquine, tell your doctor about any other medical conditions that you have, especially liver disease, kidney disease, or a seizure disorder. You may need a lower dose or special monitoring if you have any of these conditions.


Oxamniquine is in the FDA pregnancy category C. This means that it is not known whether it will harm an unborn baby. Do not take oxamniquine without first talking to your doctor if you are pregnant. It is also not known whether oxamniquine passes into breast milk and how it might affect a nursing baby. Do not take oxamniquine without first talking to your doctor if you are breast-feeding a baby.

How should I take Vansil (oxamniquine)?


Take oxamniquine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.


Take each dose with a full glass of water. Take oxamniquine with food to lessen stomach upset.

Oxamniquine is usually taken in one or two doses that completely treat the infection.


Store oxamniquine at room temperature away from moisture and heat.

What happens if I miss a dose?


Since only one or two doses are needed to treat this infection, you are not likely to miss a dose.


What happens if I overdose?


Seek emergency medical attention or call a poison control center near you.

What should I avoid while taking Vansil (oxamniquine)?


Use caution when driving, operating machinery, or performing other hazardous activities. Oxamniquine may cause dizziness. If you experience dizziness, avoid these activities.

Vansil (oxamniquine) side effects


Stop taking oxamniquine and seek emergency medical attention if you experience an allergic reaction (swelling of your lips, tongue, or face; shortness of breath; closing of your throat; or hives).

Rarely, seizures have occurred, most often in patients who already have epilepsy or another seizure disorder. Seek medical attention in the case of a seizure.


Other, less serious side effects may be more likely to occur. Continue to take oxamniquine and talk to your doctor if you experience



  • a headache, dizziness, or drowsiness; or




  • abdominal pain, decreased appetite, or vomiting.



Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.


What other drugs will affect Vansil (oxamniquine)?


Drug interactions with oxamniquine are not well known. Tell your doctor and pharmacist about all medicines you are taking, so that they can monitor your therapy for interactions.



More Vansil resources


  • Vansil Drug Interactions
  • Vansil Support Group
  • 0 Reviews for Vansil - Add your own review/rating


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Where can I get more information?


  • Your pharmacist has more information about oxamniquine written for health professionals that you may read.

What does my medication look like?


Oxamniquine is available with a prescription under the brand name Vansil in 250 mg capsules. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.



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Definition of Actinomycosis: Actinomycosis is a chronic infection, commonly of the face and neck, that produces abscesses and open draining sinuses.

Drugs associated with Actinomycosis

The following drugs and medications are in some way related to, or used in the treatment of Actinomycosis. This service should be used as a supplement to, and NOT a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

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Drug List: